Abeta 1-40 antibody

Catalog No. ABIN7265578

Product Details anti-Abeta 1-40 Antibody

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Abeta 1-40 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: APP Rabbit pAb

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human APP.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Abeta 1-40

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Alternative Name: beta-Amyloid 1-40 (Abeta 1-40 Products)

Synonyms: AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, amyloid beta precursor protein antibody, APP antibody

Background: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.,AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN-II,PN2,Amyloid beta A4,APP,Aβ42,preA4,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,β-Amyloid 1-40

Molecular Weight: 34kDa/72-86kDa

Gene ID: 351

UniProt: P05067