Angiotensin II Type 2 Receptor antibody (AA 250-350)

Catalog No. ABIN7265597

Product Details anti-Angiotensin II Type 2 Receptor Antibody

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Binding Specificity: AA 250-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiotensin II Type 2 Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: AGTR2 Rabbit pAb

Sequence: TRDQVLKMAA AVVLAFIICW LPFHVLTFLD ALAWMGVINS CEVIAVIDLA LPFAILLGFT NSCVNPFLYC FVGNRFQQKL RSVFRVPITW LQGKRESMSC R

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human AGTR2 (NP_000677.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Angiotensin II Type 2 Receptor

Target: Angiotensin II Type 2 Receptor (AGTR2) (Angiotensin II Receptor, Type 2 (AGTR2))

Alternative Name: AGTR2 (AGTR2 Products)

Synonyms: AT2 antibody, ATGR2 antibody, MRX88 antibody, AI316812 antibody, AW107640 antibody, AT2-R antibody, AT2R antibody, AT₂R antibody, at2 antibody, zgc:113016 antibody, AGTR2 antibody, angiotensin II receptor type 2 antibody, angiotensin II receptor, type 2 antibody, AGTR2 antibody, Agtr2 antibody, agtr2 antibody

Background: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.,AGTR2,AT2,ATGR2,MRX88,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Cardiovascular,Blood,Blood Pressure regulation,AGTR2

Molecular Weight: 41kDa

Gene ID: 186

UniProt: P50052

Pathways: ACE Inhibitor Pathway, Hormone Transport, Regulation of Systemic Arterial Blood Pressure by Hormones