This gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans.,CART,CARTPT,Cell Biology & Developmental Biology,Cytoskeleton,Endocrine & Metabolism,Extracellular Matrix,Extracellular Matrix_Bone,Kinase,Neuroscience,Signal Transduction,CARTPT