Filamin A antibody (C-Term)

Catalog No. ABIN7267206

Product Details anti-Filamin A Antibody

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filamin A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: Filamin A Rabbit pAb

Sequence: KYGGPYHIGG SPFKAKVTGP RLVSNHSLHE TSSVFVDSLT KATCAPQHGA PGPGPADASK VVAKGLGLSK AYVGQKSSFT VDCSKAGNNM LLVGVHGPRT PCEEILVKHV GSRLYSVSYL LKDKGEYTLV VKWGDEHIPG SPYRVVVP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 2500 to the C-terminus of human Filamin A (NP_001104026.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Alternative Name: FLNA (FLNA Products)

Synonyms: ABP-280 antibody, ABPX antibody, CSBS antibody, CVD1 antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FMD antibody, MNS antibody, NHBP antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody, fb98b06 antibody, wu:fb98b06 antibody, wu:fd09g03 antibody, wu:fd49a06 antibody, Dilp2 antibody, F730004A14Rik antibody, Fln1 antibody, filamin-1 antibody, RGD1560614 antibody, MGC147094 antibody, CG3937 antibody, Cher antibody, Dmel\\CG3937 antibody, Fil antibody, joy antibody, sko antibody, filamin A antibody, filamin A, alpha (actin binding protein 280) antibody, filamin, alpha antibody, filamin-A antibody, cheerio antibody, FLNA antibody, flna antibody, Flna antibody, LOC587317 antibody, cher antibody, LOC100380643 antibody

Background: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.,FLNA,ABP-280,ABPX,CSBS,CVD1,FLN,FLN-A,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2,XLVD,XMVD,filamin-A,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,FLNA

Molecular Weight: 280kDa

Gene ID: 2316

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location