HERC4 antibody (AA 400-700)

Catalog No. ABIN7267594

Product Details anti-HERC4 Antibody

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Binding Specificity: AA 400-700

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC4 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: [KO Validated] HERC4 Rabbit pAb

Sequence: WTVNEALIQK WLSYPSGRFP VEIANEIDGT FSSSGCLNGS FLAVSNDDHY RTGTRFSGVD MNAARLLFHK LIQPDHPQIS QQVAASLEKN LIPKLTSSLP DVEALRFYLT LPECPLMSDS NNFTTIAIPF GTALVNLEKA PLKVLENWWS VLEPPLFLKI VELFKEVVVH LLKLYKIGIP PSERRIFNSF LHTALKVLEI LHRVNEKMGQ IIQYDKFYIH EVQELIDIRN DYINWVQQQA YGMLADIPVT ICTYPFVFDA QAKTTLLQTD AVLQMQMAID QAHRQNVSSL FLPVIESVNP C

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Grade: KO Validated

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human HERC4 (NP_056416.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HERC4

Target: HERC4 (Hect Domain and RLD 4 (HERC4))

Alternative Name: HERC4 (HERC4 Products)

Synonyms: 1700056O17Rik antibody, 4921531D01Rik antibody, 9530080M15Rik antibody, mKIAA1593 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 4 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 4 S homeolog antibody, hect domain and RLD 4 antibody, HERC4 antibody, herc4 antibody, herc4.S antibody, Herc4 antibody

Background: HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008],HERC4,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,HERC4

Molecular Weight: 12kDa/13kDa/106kDa/109kDa/117kDa/118kDa

Gene ID: 26091

UniProt: Q5GLZ8