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MBP antibody

Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7268431
  • Target See all MBP products
    MBP
    Reactivity
    • 57
    • 42
    • 39
    • 4
    • 3
    Human
    Host
    • 54
    • 8
    • 2
    Rabbit
    Clonality
    • 51
    • 13
    Monoclonal
    Conjugate
    • 22
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This MBP antibody is un-conjugated
    Application
    • 35
    • 29
    • 26
    • 26
    • 22
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purpose
    Myelin Basic Protein Rabbit mAb
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Myelin Basic Protein
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MBP
    Abstract
    MBP Products
    Synonyms
    C76307 antibody, Hmbpr antibody, R75289 antibody, golli-mbp antibody, mld antibody, shi antibody, Mbps antibody, cb274 antibody, fj33b11 antibody, mbp antibody, wu:fj33b11 antibody, wu:fq15b02 antibody, zgc:136630 antibody, myelin basic protein antibody, myelin basic protein a antibody, MBP antibody, Mbp antibody, mbpa antibody
    Background
    The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008],MBP; myelin basic protein,Cell Adhesion,Cell Biology & Developmental Biology,Cell Type Marker,Cell Type Marker_Oligodendrocyte marker,Neuroscience,Stem Cells,MBP
    Molecular Weight
    18kDa
    Gene ID
    4155
    UniProt
    P02686
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