NFATC2IP antibody (AA 290-360)

Catalog No. ABIN7268978

Product Details anti-NFATC2IP Antibody

Target: NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))

Binding Specificity: AA 290-360

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC2IP antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: NFATC2IP Rabbit pAb

Sequence: VDHMATHLGV SPSRILLLFG ETELSPTATP RTLKLGVADI IDCVVLTSSP EATETSQQLQ LRVQGKEKHQ T

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 290-360 of human NFATC2IP (NP_116204.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NFATC2IP

Target: NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))

Alternative Name: NFATC2IP (NFATC2IP Products)

Synonyms: wu:fj84d09 antibody, NFATC2IP antibody, D7Ertd304e antibody, NIP45 antibody, ESC2 antibody, RAD60 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein antibody, nuclear factor of activated T-cells 2 interacting protein antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein antibody, nfatc2ip antibody, NFATC2IP antibody, Nfatc2ip antibody

Background: In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter, this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.,NFATC2IP,ESC2,NIP45,RAD60,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,NFATC2IP

Molecular Weight: 13kDa/15kDa/45kDa

Gene ID: 84901

UniProt: Q8NCF5