NUDT5 antibody

Catalog No. ABIN7269071

Product Details anti-NUDT5 Antibody

Target: NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NUDT5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: NUDT5 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human NUDT5.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NUDT5

Target: NUDT5 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 5 (NUDT5))

Alternative Name: NUDT5 (NUDT5 Products)

Synonyms: YSA1 antibody, YSA1H antibody, YSAH1 antibody, hYSAH1 antibody, NUDT5 antibody, wu:fe48a12 antibody, zgc:86930 antibody, nudix hydrolase 5 antibody, nudix hydrolase 5 L homeolog antibody, nudix (nucleoside diphosphate linked moiety X)-type motif 5 antibody, NUDT5 antibody, Nudt5 antibody, nudt5.L antibody, nudt5 antibody

Background: This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates, including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP. Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues, resulting in the inhibition of ATP-activated potassium channels. 8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA. Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors.,NUDT5, YSA1, YSA1H, YSAH1, hNUDT5, nudix hydrolase 5,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,NUDT5

Molecular Weight: 30kDa

Gene ID: 11164

UniProt: Q9UKK9