PTPRK antibody (AA 600-750)

Catalog No. ABIN7269702

Product Details anti-PTPRK Antibody

Target: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Binding Specificity: AA 600-750

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRK antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: PTPRK Rabbit pAb

Sequence: EGVDASLNET ATTITVLLRP AQAKGAPISA YQIVVEELHP HRTKREAGAM ECYQVPVTYQ NAMSGGAPYY FAAELPPGNL PEPAPFTVGD NRTYQGFWNP PLAPRKGYNI YFQAMSSVEK ETKTQCVRIA TKAAATEEPE VIPDPAKQTD R

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 600-750 of human PTPRK (NP_001129120.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTPRK

Target: PTPRK (Protein Tyrosine Phosphatase Receptor Type K (PTPRK))

Alternative Name: PTPRK (PTPRK Products)

Synonyms: R-PTP-kappa antibody, Rptpk antibody, AI853699 antibody, PTPk antibody, RPTPkappa antibody, protein tyrosine phosphatase, receptor type K antibody, protein tyrosine phosphatase, receptor type, K antibody, PTPRK antibody, Ptprk antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.,PTPRK,R-PTP-kappa,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,PTPRK

Molecular Weight: 162kDa/163kDa/164kDa

Gene ID: 5796

UniProt: Q15262

Pathways: Cell-Cell Junction Organization