SNTA1 antibody

Catalog No. ABIN7270691

Product Details anti-SNTA1 Antibody

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SNTA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: Syntrophin alpha 1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Syntrophin alpha 1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SNTA1

Target: SNTA1 (Syntrophin, alpha 1 (Dystrophin-Associated Protein A1, 59kDa, Acidic Component) (SNTA1))

Alternative Name: SNTA1 (SNTA1 Products)

Synonyms: SNTA1 antibody, MGC147484 antibody, AW228934 antibody, Snt1 antibody, LQT12 antibody, SNT1 antibody, TACIP1 antibody, dJ1187J4.5 antibody, syntrophin alpha 1 antibody, syntrophin, alpha 1 L homeolog antibody, syntrophin, alpha 1 antibody, syntrophin, acidic 1 antibody, SNTA1 antibody, snta1.L antibody, snta1 antibody, Snta1 antibody

Background: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013],LQT12, SNT1, TACIP1, dJ1187J4.5,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,SNTA1

Molecular Weight: 54kDa

Gene ID: 6640

UniProt: Q13424

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development