MAFK antibody

Catalog No. ABIN7270896

Product Details anti-MAFK Antibody

Target: MAFK (Transcription Factor MafK (MAFK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAFK antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: MAFK Rabbit pAb

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide of Human MAFK.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MAFK

Target: MAFK (Transcription Factor MafK (MAFK))

Alternative Name: MAFK (MAFK Products)

Synonyms: NFE2U antibody, P18 antibody, AW061068 antibody, NF-E2 antibody, Nfe2u antibody, MAF bZIP transcription factor K antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K antibody, Mafk antibody, MAFK antibody, mafk antibody

Background: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 609806) and ferrochelatase (FECH, MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM, Nov 2008],NFE2U,P18,MAFK,Epigenetics & Nuclear Signaling,Transcription Factors,MAFK

Gene ID: 7975

UniProt: O60675