B4GALT3 antibody (AA 40-150)

Catalog No. ABIN7271199

Product Details anti-B4GALT3 Antibody

Target: B4GALT3 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 3 (B4GALT3))

Binding Specificity: AA 40-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B4GALT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purpose: B4GALT3 Rabbit pAb

Sequence: RDQGPTFDYS HPRDVYSNLS HLPGAPGGPP APQGLPYCPE RSPLLVGPVS VSFSPVPSLA EIVERNPRVE PGGRYRPAGC EPRSRTAIIV PHRAREHHLR LLLYHLHPFL Q

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-150 of human B4GALT3 (NP_003770.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for B4GALT3

Target: B4GALT3 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 3 (B4GALT3))

Alternative Name: B4GALT3 (B4GALT3 Products)

Synonyms: beta4Gal-T3 antibody, 9530061M23Rik antibody, AA104562 antibody, AW125175 antibody, ESTM26 antibody, ESTM6 antibody, R74981 antibody, b4Gal-T3 antibody, beta-1,4-galactosyltransferase 3 antibody, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 S homeolog antibody, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 antibody, B4GALT3 antibody, b4galt3.S antibody, B4galt3 antibody

Background: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010],B4GALT3,beta4Gal-T3,beta-1,B4GALT3

Molecular Weight: 15kDa/43kDa

Gene ID: 8703

UniProt: O60512

Pathways: Glycosaminoglycan Metabolic Process