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SCN8A antibody (AA 251-314)

SCN8A Reactivity: Human, Mouse WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN719981
  • Target See all SCN8A Antibodies
    SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
    Binding Specificity
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-314
    Reactivity
    • 30
    • 25
    • 13
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 29
    • 5
    Rabbit
    Clonality
    • 29
    • 5
    Polyclonal
    Conjugate
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SCN8A antibody is un-conjugated
    Application
    • 31
    • 12
    • 12
    • 12
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SCN8A/Nav1.6
    Isotype
    IgG
    Top Product
    Discover our top product SCN8A Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
    Alternative Name
    SCN8A (SCN8A Products)
    Synonyms
    CERIII antibody, CIAT antibody, EIEE13 antibody, MED antibody, NaCh6 antibody, Nav1.6 antibody, PN4 antibody, AI853486 antibody, C630029C19Rik antibody, dmu antibody, med antibody, mnd-2 antibody, mnd2 antibody, nmf2 antibody, nmf335 antibody, nmf58 antibody, nur14 antibody, seal antibody, sodium voltage-gated channel alpha subunit 8 antibody, sodium channel, voltage-gated, type VIII, alpha antibody, SCN8A antibody, Scn8a antibody
    Background

    Synonyms: CerIII, hNa6/Scn8a voltage gated sodium channel, MED, Motor endplate disease, NaCh 6, NaCh6, Nav 1.6, Nbna1, PN 4, PN4, Scn8a, SCN8A_HUMAN, Sodium channel protein type 8 alpha subunit, Sodium channel protein type 8 subunit alpha, Sodium channel protein type VIII alpha subunit, Sodium channel protein type VIII subunit alpha, Sodium channel voltage gated type VIII alpha, Sodium channel voltage gated type VIII alpha polypeptide, Sodium channel voltage gated type VIII alpha subunit, Voltage gated sodium channel subunit alpha Nav1.6, Voltage-gated sodium channel subunit alpha Nav1.6.

    Background: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

    Gene ID
    6334
    Pathways
    Sensory Perception of Sound
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