MVP antibody (AA 2-259) (DyLight 488)

Catalog No. ABIN7600482

This Mouse Monoclonal antibody specifically detects MVP in FACS. It exhibits reactivity toward Human.

Quick Overview for MVP antibody (AA 2-259) (DyLight 488) (ABIN7600482)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MVP antibody is conjugated to DyLight 488

Application: Flow Cytometry (FACS)

Clone: 8B12

Product Details anti-MVP Antibody (DyLight 488)

Binding Specificity: AA 2-259

Purpose: Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12)

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Human MVP DyLight® 488 conjugated Antibody (monoclonal, 8B12) -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: E. coli-derived human MVP recombinant protein (Position: A2-H259).

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, human
1. "Entrez Gene: MVP major vault protein". 2. Izquierdo MA, Scheffer GL, Flens MJ, Schroeijers AB, van der Valk P, Scheper RJ (Jun 1996). "Major vault protein LRP-related multidrug resistance". European Journal of Cancer. 32A (6): 979-84.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: MVP

Background:

Synonyms: Major vault protein, MVP, Lung resistance-related protein, MVP, LRP

Background: Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

Molecular Weight: 39 kDa

Gene ID: 9961

UniProt: Q14764