PKN2 antibody (AA 881-984)

Catalog No. ABIN729283

Product Details anti-PKN2 Antibody

Target: PKN2 (Protein Kinase N2 (PKN2))

Binding Specificity: AA 881-984

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKN2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PKN2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PKN2

Target: PKN2 (Protein Kinase N2 (PKN2))

Alternative Name: PKN2 (PKN2 Products)

Synonyms: PAK2 antibody, PRK2 antibody, PRKCL2 antibody, PRO2042 antibody, Pak-2 antibody, 6030436C20Rik antibody, AI507382 antibody, Prkcl2 antibody, Stk7 antibody, pak2 antibody, prk2 antibody, pak-2 antibody, pro2042 antibody, PKN2 antibody, si:ch211-83f14.1 antibody, wu:fa97c07 antibody, protein kinase N2 antibody, protein kinase N2 L homeolog antibody, PKN2 antibody, Pkn2 antibody, pkn2.L antibody, pkn2 antibody

Background:

Synonyms: protein kinase N2, Serine/threonine-protein kinase N2, Protein kinase C-like 2, Protease-activated kinase 2, PAK-2, Cardiolipin activated protein kinase Pak2, MGC150606, MGC71074, PAK2, PRK2, PRKCL2, PRO2042, Protein kinase C like 2, Protein kinase C related kinase 2.

Background: Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis

Gene ID: 5586

Pathways: Cell-Cell Junction Organization