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Leptin Receptor antibody (AA 501-600)

LEPR Reactivity: Human, Mouse, Rat WB, FACS, IF (p), IHC (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN730303
  • Target See all Leptin Receptor (LEPR) Antibodies
    Leptin Receptor (LEPR)
    Binding Specificity
    • 16
    • 15
    • 11
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    Reactivity
    • 114
    • 70
    • 49
    • 20
    • 12
    • 5
    • 4
    • 2
    Human, Mouse, Rat
    Host
    • 116
    • 15
    • 2
    • 2
    • 1
    • 1
    Rabbit
    Clonality
    • 113
    • 24
    Polyclonal
    Conjugate
    • 50
    • 11
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    This Leptin Receptor antibody is un-conjugated
    Application
    • 87
    • 47
    • 35
    • 35
    • 26
    • 25
    • 16
    • 10
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human of human Leptin receptor
    Isotype
    IgG
    Top Product
    Discover our top product LEPR Primary Antibody
  • Application Notes
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • De Matteis, Grandoni, Scatà, Catizone, Reale, Crisà, Moioli: "Evaluation of leptin receptor expression on buffalo leukocytes." in: Veterinary immunology and immunopathology, Vol. 177, pp. 16-23, (2016) (PubMed).

  • Target
    Leptin Receptor (LEPR)
    Alternative Name
    Leptin Receptor (LEPR Products)
    Synonyms
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    Background

    Synonyms: OBR, OB-R, CD295, LEP-R, LEPRD, Leptin receptor, HuB219, OB receptor, LEPR, DB

    Background: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).

    Gene ID
    3953
    UniProt
    P48357
    Pathways
    JAK-STAT Signaling, AMPK Signaling, Feeding Behaviour
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