Decorin antibody (AA 101-200)

Catalog No. ABIN733103

Product Details anti-Decorin Antibody

Target: Decorin (DCN)

Binding Specificity: AA 101-200

Reactivity: Human, Rat, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Decorin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Goat, Human, Rat

Predicted Reactivity: Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Decorin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Decorin antibody (ABIN733103)

Li, Li, Liang, Xiao, Zhang, Shao, Peng, Chen, Li, Chen: "Identifying DCN and HSPD1 as Potential Biomarkers in Colon Cancer Using 2D-LC-MS/MS Combined with iTRAQ Technology." in: Journal of Cancer, Vol. 8, Issue 3, pp. 479-489, (2017) (PubMed).

Li, Qiu, Liu, Wang, Hu, Gan, Wang: "Long-term thermal manipulation in the late incubation period can inhibit breast muscle development by activating endoplasmic reticulum stress in duck (Anasplatyrhynchos domestica)." in: Journal of thermal biology, Vol. 70, Issue Pt B, pp. 37-45, (2017) (PubMed).

Peng, Gao, Xin, Han, Zhu, Cao: "Molecular cloning, expression analysis, and function of decorin in goat ovarian granulosa cells." in: Domestic animal endocrinology, Vol. 57, pp. 108-16, (2016) (PubMed).

Bakker, Groma, Spijkers, de Vos, van Weert, van Veen, Everts, Arribas, VanBavel: "Heterogeneity in Arterial Remodeling among Sublines of Spontaneously Hypertensive Rats." in: PLoS ONE, Vol. 9, Issue 9, pp. e107998, (2014) (PubMed).

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: Decorin (DCN Products)

Synonyms: CSCD antibody, DSPG2 antibody, PG40 antibody, PGII antibody, PGS2 antibody, SLRR1B antibody, DC antibody, mDcn antibody, cscd antibody, dspg2 antibody, pg40 antibody, pgii antibody, pgs2 antibody, slrr1b antibody, decorin antibody, decorin L homeolog antibody, DCN antibody, Dcn antibody, dcn.L antibody, dcn antibody

Background:

Synonyms: CSCD, PG4, PGII, PGS2, DSPG2, SLRR1B, Decorin, Bone proteoglycan II, PG-S2, DCN

Background: Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes. Also known as: Decorin, Bone proteoglycan II, CSCD, DCN, DCN protein, Dermatan sulphate proteoglycans II, DKFZp686J19238, DSPG 2, DSPG2, PG 40, PG II, PG S2, PG40, PGII, PGS 2, PGS2, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B.

Gene ID: 1634

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process