PFN2 antibody (AA 51-140) (Biotin)

Catalog No. ABIN735730

Product Details anti-PFN2 Antibody (Biotin)

Target: PFN2 (Profilin 2 (PFN2))

Binding Specificity: AA 51-140

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFN2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody may detect Profilin 1 due to a 71 % amino acid sequence similarity in the immunogen sequence.

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat Profilin 2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PFN2

Target: PFN2 (Profilin 2 (PFN2))

Alternative Name: Profilin 2 (PFN2 Products)

Synonyms: D3S1319E antibody, PFL antibody, Pfn antibody, Profilin2 antibody, XProfilin2 antibody, PFN2 antibody, PRO2 antibody, Profilin-2 antibody, pfl antibody, d3s1319e antibody, profilin-2 antibody, F17A13.170 antibody, F17A13_170 antibody, PRF2 antibody, PROFILIN antibody, PROFILIN 2 antibody, profilin 2 antibody, wu:fb01g08 antibody, wu:fb54f09 antibody, wu:fd58f06 antibody, profilin 2 antibody, profilin 2 L homeolog antibody, profilin homolog 2 antibody, Profilin-2 antibody, PFN2 antibody, Pfn2 antibody, pfn2.L antibody, prf2 antibody, pfn2 antibody, pfn-2 antibody

Background:

Synonyms: Profilin-2, Profilin II, Pfn2

Background: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).

Gene ID: 81531

UniProt: Q9EPC6

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis