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Influenza A Matrix Protein 2 antibody (Influenza A Virus) (AA 2-60) (Biotin)

M2 Reactivity: Influenza A Virus, Virus ELISA, IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN739061
  • Target See all Influenza A Matrix Protein 2 (M2) Antibodies
    Influenza A Matrix Protein 2 (M2)
    Binding Specificity
    • 14
    • 6
    AA 2-60
    Reactivity
    • 15
    • 14
    • 2
    • 1
    • 1
    • 1
    Influenza A Virus, Virus
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Biotin
    Application
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody will recognize many Influenza A virus strains
    Cross-Reactivity
    Virus
    Cross-Reactivity (Details)
    Influenza A virus
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from Influenza A virus H5N1 Matrix Protein-2
    Isotype
    IgG
    Top Product
    Discover our top product M2 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Influenza A Matrix Protein 2 (M2)
    Alternative Name
    Influenza A virus Matrix Protein 2 (M2 Products)
    Synonyms
    matrix protein 2 antibody
    Target Type
    Influenza Protein
    Background

    Synonyms: Avian influenza Matrix Protein-2, Influenza A virus H7N7 H9N2 H13N6 H16N3 H1N1 N2N1 H3N2 H2N2

    Background: Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry. After attaching to the cell surface, the virion enters the cell by endocytosis. Acidification of the endosome triggers M2 ion channel activity. The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur. Also plays a role in viral proteins secretory pathway. Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation

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