KLRC1 antibody (AA 8-100)

Catalog No. ABIN739875

Product Details anti-KLRC1 Antibody

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Binding Specificity: AA 8-100

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NKG2A

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-KLRC1 antibody (ABIN739875)

Zou, Zuo, Yang, Fan: "The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells." in: Biochemical and biophysical research communications, Vol. 478, Issue 1, pp. 213-20, (2016) (PubMed).

Hall, Murphy, Quinlan, Hurley, Shanahan, Nally, Melgar: "Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor." in: Mucosal immunology, Vol. 6, Issue 5, pp. 1016-26, (2013) (PubMed).

Target Details for KLRC1

Target: KLRC1 (Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))

Alternative Name: NKG2A (KLRC1 Products)

Background:

Synonyms: NKG2, NKG2A, CD159A, NKG2-A/NKG2-B type II integral membrane protein, CD159 antigen-like family member A, NK cell receptor A, NKG2-A/B-activating NK receptor, KLRC1

Background: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Gene ID: 3821

UniProt: P26715