NCR3 antibody (AA 81-180)

Catalog No. ABIN739980

Product Details anti-NCR3 Antibody

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Binding Specificity: AA 81-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCR3 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCR3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for NCR3

Target: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Alternative Name: NCR3 (NCR3 Products)

Synonyms: MGC133750 antibody, 1C7 antibody, CD337 antibody, LY117 antibody, MALS antibody, NKp30 antibody, Nkp30 antibody, natural cytotoxicity triggering receptor 3 antibody, NCR3 antibody, Ncr3 antibody

Background:

Synonyms: 1C7, MALS, CD337, LY117, NKp30, Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NCR3

Background: Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Gene ID: 259197

UniProt: O14931

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process