CLEC5A antibody (AA 101-190) (Cy5)

Catalog No. ABIN748767

Product Details anti-CLEC5A Antibody (Cy5)

Target: CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))

Binding Specificity: AA 101-190

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC5A antibody is conjugated to Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse CLEC5A

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CLEC5A

Target: CLEC5A (C-Type Lectin Domain Family 5, Member A (CLEC5A))

Alternative Name: CLEC5A (CLEC5A Products)

Synonyms: CLECSF5 antibody, MDL-1 antibody, MDL1 antibody, Clecsf5 antibody, Ly100 antibody, Mdl1 antibody, C-type lectin domain containing 5A antibody, C-type lectin domain family 5, member a antibody, CLEC5A antibody, Clec5a antibody

Background:

Synonyms: Mdl1, Ly100, MDL-1, Clecsf5, C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, Clec5a

Background: Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.

Gene ID: 23845

UniProt: Q9R007