CACNA1D antibody (AA 1201-1300)

Catalog No. ABIN751333

Product Details anti-CACNA1D Antibody

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Binding Specificity: AA 1201-1300

Reactivity: Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACNA1D antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Monkey, Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CaV1.3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-CACNA1D antibody (ABIN751333)

Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." in: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

Target Details for CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Alternative Name: CACH3/CaV1.3 (CACNA1D Products)

Synonyms: cacna1d antibody, cav1.3a antibody, isl antibody, si:dz136d19.3 antibody, si:dz223c6.1 antibody, ca(v)1.3 antibody, cav1.3 antibody, CACH3 antibody, CACN4 antibody, CACNL1A2 antibody, CCHL1A2 antibody, Cav1.3 antibody, SANDD antibody, 8430418G19Rik antibody, C79217 antibody, Cacnl1a2 antibody, Cchl1a antibody, Cchl1a2 antibody, D-LTCC antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit, a antibody, calcium voltage-gated channel subunit alpha1 D antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit antibody, calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog antibody, cacna1da antibody, CACNA1D antibody, cacna1d antibody, cacna1d.L antibody, Cacna1d antibody

Background:

Synonyms: CACH3, CACN4, PASNA, SANDD, Cav1.3, CCHL1A2, CACNL1A2, Voltage-dependent L-type calcium channel subunit alpha-1D, Calcium channel, L type, alpha-1 polypeptide, isoform 2, Voltage-gated calcium channel subunit alpha Cav1.3, CACNA1D

Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).

Gene ID: 776

UniProt: Q01668

Pathways: Sensory Perception of Sound