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CACNA1E antibody (AA 1265-1360) (Cy5.5)

CACNA1E Reactivity: Human IF (p), IF (cc) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN751353
  • Target See all CACNA1E Antibodies
    CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1265-1360
    Reactivity
    • 20
    • 4
    • 4
    • 1
    Human
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA1E antibody is conjugated to Cy5.5
    Application
    • 12
    • 12
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cav23
    Isotype
    IgG
    Top Product
    Discover our top product CACNA1E Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))
    Alternative Name
    CACH6/Cav2.3 (CACNA1E Products)
    Synonyms
    caV2.3 antibody, CACNA1E antibody, BII antibody, CACH6 antibody, CACNL1A6 antibody, Cav2.3 antibody, A430040I15 antibody, Cach6 antibody, Cacnl1a6 antibody, Cchra1 antibody, alpha1E antibody, CACHA1E antibody, calcium voltage-gated channel subunit alpha1 E antibody, calcium channel, voltage-dependent, R type, alpha 1E subunit antibody, CACNA1E antibody, cacna1e antibody, Cacna1e antibody
    Background

    Synonyms: BII, Brain calcium channel II, CAC 1E, CAC1E, CACH 6, CACH6, CACNA1E, Cacnl1 a6, CACNL1A6, Calcium channel, L type, alpha 1 polypeptide, isoform 6, calcium channel, R type, Cav 2.3, Cchra 1, Cchra1, Voltage dependent R type calcium channel subunit alpha 1E, Voltage gated calcium channel subunit alpha Cav2.3.

    Background: Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.

    Gene ID
    777
    Pathways
    Carbohydrate Homeostasis
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