SDHD antibody (AA 81-159)

Catalog No. ABIN751918

Product Details anti-SDHD Antibody

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Binding Specificity: AA 81-159

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHD antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SDHD

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SDHD antibody (ABIN751918)

Huang, Wang, Xie, Pang, Wang, Yi, Zhang, Zhang, Chen, Lan, Zhang, Jiang: "Germline SDHB and SDHD mutations in pheochromocytoma and paraganglioma patients." in: Endocrine connections, Vol. 7, Issue 12, pp. 1217-1225, (2018) (PubMed).

Target Details for SDHD

Target: SDHD (Succinate Dehydrogenase Complex, Subunit D, Integral Membrane Protein (SDHD))

Alternative Name: SDHD (SDHD Products)

Background:

Synonyms: Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial, CybS, CII-4, QPs3, Succinate dehydrogenase complex subunit D, Succinate-ubiquinone oxidoreductase cytochrome b small subunit, Succinate-ubiquinone reductase membrane anchor subunit, SDHD, SDH4

Background: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Gene ID: 6392

UniProt: O14521