PTPRA antibody (AA 151-250) (Cy3)

Catalog No. ABIN754636

This Rabbit Polyclonal antibody specifically detects PTPRA in IF (p) and IF (cc). It exhibits reactivity toward Rat.

Quick Overview for PTPRA antibody (AA 151-250) (Cy3) (ABIN754636)

Target: PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRA antibody is conjugated to Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-PTPRA Antibody (Cy3)

Binding Specificity: AA 151-250

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PTPRA

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PTPRA

Target: PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))

Alternative Name: PTPRA

Background:

Synonyms: LRP, HLPR, PTPA, HEPTP, HPTPA, RPTPA, PTPRL2, HPTPalpha, R-PTP-alpha, Receptor-type tyrosine-protein phosphatase alpha, Protein-tyrosine phosphatase alpha, PTPRA

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]

Gene ID: 5786

UniProt: P18433