DAB2IP antibody (AA 901-1069) (HRP)

Catalog No. ABIN760955

Product Details anti-DAB2IP Antibody (HRP)

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Binding Specificity: AA 901-1069

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB2IP antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAB2IP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DAB2IP

Target: DAB2IP (DAB2 Interacting Protein (DAB2IP))

Alternative Name: DAB2IP (DAB2IP Products)

Synonyms: dab2ip antibody, wu:fc08b07 antibody, wu:fk62h05 antibody, AF9Q34 antibody, AIP-1 antibody, AIP1 antibody, DIP1/2 antibody, 2310011D08Rik antibody, AI480459 antibody, Aip1 antibody, mKIAA1743 antibody, disabled homolog 2-interacting protein antibody, DAB2 interacting protein antibody, DAB2 interacting protein b antibody, disabled 2 interacting protein antibody, LOC100071680 antibody, DAB2IP antibody, dab2ipb antibody, dab2ip antibody, Dab2ip antibody

Background:

Synonyms: AF9Q34, AIP1, ASK interacting protein, DAB2P_HUMAN, ASK interacting protein 1, ASK1 interacting protein 1, DAB2 interacting protein, DAB2 interaction protein, DAB2P, DIP1/2, Disabled homolog 2 interacting protein, DOC 2/DAB2 interactive protein, FLJ39072, KIAA1743, nGAP like protein.

Background: DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers. It also interacts with MAP3K5 to disrupt the association of MAP3K5 with the inhibitory 14-3-3 complex.

Gene ID: 153090

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Tube Formation