NBL1 antibody (AA 75-180) (Biotin)

Catalog No. ABIN761593

Product Details anti-NBL1 Antibody (Biotin)

Target: NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))

Binding Specificity: AA 75-180

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NBL1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NBL1/DAND1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NBL1

Target: NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))

Alternative Name: NBL1 (NBL1 Products)

Synonyms: D1S1733E antibody, DAN antibody, DAND1 antibody, NB antibody, NO3 antibody, D4H1S1733E antibody, Dana antibody, dand1 antibody, nbl1-a antibody, no3 antibody, 4.1N antibody, Epb41l1 antibody, NBL1 antibody, mKIAA0338 antibody, C1orf151-NBL1 antibody, dan antibody, zgc:77251 antibody, neuroblastoma 1, DAN family BMP antagonist antibody, neuroblastoma, suppression of tumorigenicity 1 antibody, neuroblastoma 1, DAN family BMP antagonist L homeolog antibody, neuroblastoma suppressor of tumorigenicity 1 antibody, erythrocyte membrane protein band 4.1 like 1 antibody, MINOS1-NBL1 readthrough antibody, NBL1 antibody, Nbl1 antibody, nbl1.L antibody, LOC535280 antibody, Epb41l1 antibody, MINOS1-NBL1 antibody, nbl1 antibody

Background:

Synonyms: DAN domain family member 1, DAN antibody DAND 1, DAND1, Dferential screening selected gene aberrant in neuroblastoma, NB antibody NBL 1, Neuroblastoma candidate region suppression of tumorigenicity 1, Neuroblastoma suppression of tumorigenicity 1, Neuroblastoma suppressor of tumorigenicity 1, NO 3, NO3, Zinc finger protein DAN.

Background: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.

Gene ID: 4681