PKD1 antibody (AA 2281-2292)

Catalog No. ABIN768558

Product Details anti-PKD1 Antibody

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Binding Specificity: AA 2281-2292

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This PKD1 antibody is un-conjugated

Application: ELISA

Purpose: PKD1 (aa2281-2292)

Sequence: KSYDPNLEDG DQT

Specificity: This antibody is expected to recognize both reported isoforms (NP_001009944.2, NP_000287.3).

Predicted Reactivity: Human, Mouse, Rat, Dog, Pig

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Recent

Immunogen: Peptide with sequence C-KSYDPNLEDGDQT, from the C Terminus of the protein sequence according to NP_001009944.2, NP_000287.3.

Isotype: IgG

Application Details

Application Notes:

DS WB Results: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 463 kDa according to NP_000287.3. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.

Peptide ELISA: antibody detection limit dilution 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for PKD1

Target: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Alternative Name: PKD1 (PKD1 Products)

Synonyms: PBP antibody, Pc-1 antibody, TRPP1 antibody, PC1 antibody, mFLJ00285 antibody, polycystin 1, transient receptor potential channel interacting antibody, polycystin 1, transient receptor poteintial channel interacting antibody, polycystin-1 antibody, PKD1 antibody, Pkd1 antibody, LOC749291 antibody

Background: PKD1, polycystic kidney disease 1 (autosomal dominant), PBP, Pc-1, TRPP1, autosomal dominant polycystic kidney disease 1 protein, polycystic kidney disease-associated protein, polycystin 1, polycystin-1, transient receptor potential cation channel, subfamily P, member 1

Molecular Weight: 463kDa

Gene ID: 5310

NCBI Accession: NP_001009944, NP_000287

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location