CRY1 antibody (AA 551-555)

Catalog No. ABIN783298

Product Details anti-CRY1 Antibody

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Binding Specificity: AA 551-555

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRY1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: S-Q-G-S-G

Specificity: This antibody detects endogenous level of total CRY1 protein.

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Purification: Affinity-chromatography using epitope-specific peptide

Immunogen: Peptide sequence around aa.551~555 derived from Mouse CRY1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store (in aliquots) at -20 °C.

Target Details for CRY1

Target: CRY1 (Cryptochrome 1 (Photolyase-Like) (CRY1))

Alternative Name: Cryptochrome-1 (CRY1 Products)

Background: Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.Synonyms: CRY1, PHLL1

Molecular Weight: 60 kDa

Gene ID: 1407

NCBI Accession: NP_004066

UniProt: Q16526

Pathways: Response to Water Deprivation, Proton Transport