BCAS1 antibody (C-Term)

Catalog No. ABIN783588

Product Details anti-BCAS1 Antibody

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human BCAS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for BCAS1

Target: BCAS1 (Breast Carcinoma Amplified Sequence 1 (BCAS1))

Alternative Name: BCAS1 / NABC1 (BCAS1 Products)

Synonyms: AIBC1 antibody, NABC1 antibody, 2210416M21Rik antibody, 9030223A09Rik antibody, AI841227 antibody, Band83 antibody, Pmes-2 antibody, BCAS1 antibody, MGC152145 antibody, breast carcinoma amplified sequence 1 antibody, BCAS1 antibody, Bcas1 antibody

Background: BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines. Little is known about this protein, BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures. High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis. Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene. The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.Synonyms: AIBC1, Breast carcinoma-amplified sequence 1

Gene ID: 8537

NCBI Accession: NP_003648

UniProt: O75363