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ZC3HAV1 antibody (C-Term)

ZC3HAV1 Reactivity: Human WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783641
  • Target See all ZC3HAV1 Antibodies
    ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))
    Binding Specificity
    • 9
    • 8
    • 6
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 28
    • 2
    • 1
    Human
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZC3HAV1 antibody is un-conjugated
    Application
    • 21
    • 16
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    14 amino acid peptide near the carboxy terminus of human ZC3HAV1
    Top Product
    Discover our top product ZC3HAV1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))
    Alternative Name
    ZC3HAV1 (ZC3HAV1 Products)
    Synonyms
    1200014N16Rik antibody, 2900058M19Rik antibody, 9130009D18Rik antibody, 9830115L13Rik antibody, ARTD13 antibody, D6Bwg1452e antibody, ZAP antibody, Zap antibody, FLB6421 antibody, PARP13 antibody, ZC3H2 antibody, ZC3HDC2 antibody, zinc finger CCCH type, antiviral 1 antibody, zinc finger CCCH-type containing, antiviral 1 antibody, Zc3hav1 antibody, ZC3HAV1 antibody
    Background
    The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.Synonyms: PRO1677, ZC3HDC2, Zinc finger CCCH domain-containing protein 2, Zinc finger CCCH-type antiviral protein 1, Zinc finger antiviral protein
    Gene ID
    56829
    NCBI Accession
    NP_064504
    UniProt
    Q7Z2W4
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