ZC3HAV1 antibody (C-Term)

Catalog No. ABIN783641

The Rabbit Polyclonal anti-ZC3HAV1 antibody has been validated for WB, IF and EIA. It is suitable to detect ZC3HAV1 in samples from Human.

Quick Overview for ZC3HAV1 antibody (C-Term) (ABIN783641)

Target: ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3HAV1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-ZC3HAV1 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of human ZC3HAV1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for ZC3HAV1

Target: ZC3HAV1 (Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))

Alternative Name: ZC3HAV1

Background: The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.Synonyms: PRO1677, ZC3HDC2, Zinc finger CCCH domain-containing protein 2, Zinc finger CCCH-type antiviral protein 1, Zinc finger antiviral protein

Gene ID: 56829

NCBI Accession: NP_064504

UniProt: Q7Z2W4