ATP11B antibody (N-Term)

Catalog No. ABIN783661

Product Details anti-ATP11B Antibody

Target: ATP11B (ATPase, Class VI, Type 11B (ATP11B))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP11B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human ATP11B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for ATP11B

Target: ATP11B (ATPase, Class VI, Type 11B (ATP11B))

Alternative Name: ATP11B (ATP11B Products)

Synonyms: ATPIF antibody, ATPIR antibody, 1110019I14Rik antibody, mKIAA0956 antibody, ATP11B antibody, ATPase phospholipid transporting 11B (putative) antibody, ATPase, class VI, type 11B antibody, probable phospholipid-transporting ATPase IF antibody, ATP11B antibody, Atp11b antibody, atp11b antibody, LOC100578323 antibody

Background: ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.Synonyms: ATPIF, ATPIR, ATPase IR, ATPase class VI type 11B, KIAA0956, Probable phospholipid-transporting ATPase IF

Gene ID: 23200

NCBI Accession: NP_055431

UniProt: Q9Y2G3