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KLRA1 antibody (C-Term)

KLRA1 Reactivity: Human, Mouse, Rat WB, EIA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783823
  • Target See all KLRA1 Antibodies
    KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 4
    • 1
    Rabbit
    Clonality
    • 4
    • 1
    Polyclonal
    Conjugate
    • 5
    This KLRA1 antibody is un-conjugated
    Application
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    13 amino acid peptide near the carboxy terminus of human KLRA1
    Top Product
    Discover our top product KLRA1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    KLRA1 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 1 (KLRA1))
    Alternative Name
    KLRA1 (KLRA1 Products)
    Synonyms
    Klra2 antibody, Ly49i8 antibody, A1 antibody, Klra22 antibody, Ly49a antibody, Ly49o<129> antibody, Ly49v antibody, LY49 antibody, KLRA1 antibody, Ly49 antibody, killer cell lectin-like receptor, subfamily A, member 1 antibody, killer cell lectin-like receptor subfamily A, member 1 antibody, Klra1 antibody, KLRA1 antibody, LY49 antibody
    Background
    KLRA1 (also known and Ly49L) is a member of the LY49 family of receptors Natural killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist.Synonyms: KLRA-1, Killer cell lectin-like receptor subfamily A, LY49A, LY49L, Lymphocyte antigen 49a, T lymphocyte antigen A1, member 1
    Gene ID
    10090
    UniProt
    P20937
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