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tau antibody (pSer214) (Cy5)

Reactivity: Mouse WB, IF (p), IF (cc) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN801757
  • Target See all tau Antibodies
    tau (tau Protein)
    Binding Specificity
    • 31
    • 30
    • 30
    • 26
    • 26
    • 26
    • 24
    • 23
    • 22
    • 21
    • 19
    • 18
    • 17
    • 17
    • 17
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 11
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    pSer214
    Reactivity
    • 520
    • 500
    • 498
    • 40
    • 28
    • 27
    • 18
    • 6
    • 3
    • 2
    • 1
    • 1
    Mouse
    Host
    • 624
    • 35
    • 2
    • 1
    Rabbit
    Clonality
    • 599
    • 62
    • 1
    Polyclonal
    Conjugate
    • 208
    • 39
    • 34
    • 33
    • 33
    • 33
    • 32
    • 32
    • 31
    • 29
    • 24
    • 24
    • 24
    • 24
    • 23
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This tau antibody is conjugated to Cy5
    Application
    • 542
    • 271
    • 262
    • 200
    • 92
    • 85
    • 62
    • 59
    • 49
    • 35
    • 34
    • 15
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human Tau protein isoform TauF around the phosphorylation site of Ser214 [TP(p-S)LP]
    Isotype
    IgG
    Top Product
    Discover our top product tau Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    tau (tau Protein)
    Abstract
    tau Products
    Synonyms
    DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, tau antibody, PHF-tau antibody, microtubule associated protein tau antibody, MAPT antibody
    Background

    Synonyms: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R13, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT

    Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    Gene ID
    4137
    UniProt
    P10636
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