ASPSCR1 antibody (AA 303-307)

Catalog No. ABIN871654

Product Details anti-ASPSCR1 Antibody

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Binding Specificity: AA 303-307

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASPSCR1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous levels of total ASPSCR1 protein.

Purification: Affinity purified

Immunogen: Peptide sequence around AA 303-307 (P-Q-Q-E-Q) derived from Human ASPSCR1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Alternative Name: ASPSCR1 (ASPSCR1 Products)

Synonyms: tug antibody, aspl antibody, asps antibody, rcc17 antibody, ubxd9 antibody, aspcr1 antibody, ASPCR1 antibody, ASPL antibody, ASPS antibody, RCC17 antibody, TUG antibody, UBXD9 antibody, UBXN9 antibody, 1190006K01Rik antibody, ASPC antibody, ASPSCR1, UBX domain containing tether for SLC2A4 antibody, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antibody, alveolar soft part sarcoma chromosome region, candidate 1 antibody, alveolar soft part sarcoma chromosome region, candidate 1 (human) antibody, ASPSCR1 antibody, aspscr1.S antibody, Aspscr1 antibody, aspscr1 antibody, Bm1_55980 antibody

Background: Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.

Molecular Weight: 70-75 kDa

Gene ID: 79058

NCBI Accession: NP_076988

UniProt: Q9BZE9