CLASP1 antibody (AA 30-130)

Catalog No. ABIN872439

Product Details anti-CLASP1 Antibody

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Binding Specificity: AA 30-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLASP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLASP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CLASP1

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Alternative Name: CLASP1 (CLASP1 Products)

Synonyms: Xorbit antibody, clasp1 antibody, clasp1b antibody, mast1 antibody, CLASP1 antibody, 1700030C23Rik antibody, 5730583A19Rik antibody, B130045P17Rik antibody, mKIAA0622 antibody, MAST1 antibody, cytoplasmic linker associated protein 1 S homeolog antibody, cytoplasmic linker associated protein 1b antibody, cytoplasmic linker associated protein 1 antibody, CLIP-associating protein 1 antibody, CLIP associating protein 1 antibody, clasp1.S antibody, clasp1b antibody, CLASP1 antibody, clasp1 antibody, LOC100078792 antibody, Clasp1 antibody

Background:

Synonyms: CLAP1_HUMAN, clasp1, CLIP associating protein 1, CLIP associating protein CLASP1, CLIP-associating protein 1, Cytoplasmic linker associated protein 1, Cytoplasmic linker-associated protein 1, hOrbit1, MAST1, Multiple asters 1, Multiple asters homolog 1, Protein Orbit homolog 1.

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Gene ID: 23332

Pathways: Microtubule Dynamics, M Phase, Maintenance of Protein Location