Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SRGN antibody (AA 61-158)

SRGN Reactivity: Human ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN872475
  • Target See all SRGN Antibodies
    SRGN (serglycin (SRGN))
    Binding Specificity
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 61-158
    Reactivity
    • 24
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 26
    • 4
    Rabbit
    Clonality
    • 26
    • 4
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SRGN antibody is un-conjugated
    Application
    • 17
    • 11
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Serglycin/SRGN Polyclonal Antibody
    Isotype
    IgG
    Top Product
    Discover our top product SRGN Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    SRGN (serglycin (SRGN))
    Alternative Name
    SRGN (SRGN Products)
    Synonyms
    PPG antibody, PRG antibody, PRG1 antibody, Prg antibody, Prg1 antibody, Sgc antibody, Pgsg antibody, serglycin antibody, SRGN antibody, Srgn antibody
    Background

    Synonyms: Chondroitin sulfate proteoglycan core protein, Cytolytic granule proteoglycan core protein, Hematopoetic proteoglycan core protein, Mastocytoma proteoglycan core protein, P.PG, PG19 core protein, Pgsg, Platelet proteoglycan core protein, platelet proteoglycan protein core, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG, PRG, PRG1, PROTEOGLYCAN 1, proteoglycan 1, secretory granule, Proteoglycan 10K core protein, Proteoglycan peptide core protein, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE, secretory granule proteoglycan 1, Secretory granule proteoglycan core protein, Serglycin, serglycin proteoglycan, Sgc, Srgn, SRGN_HUMAN.

    Background: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

    Gene ID
    5552
    Pathways
    Maintenance of Protein Location
You are here:
Support