Factor VIII antibody (AA 85-190)

Catalog No. ABIN872493

Product Details anti-Factor VIII Antibody

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Binding Specificity: AA 85-190

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Factor VIII antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Factor VIII

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Factor VIII antibody (ABIN872493)

Zhu, Hua, Zhu, Li, Wang, Yu, Li: "Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135866, (2016) (PubMed).

Tang, Liu, Dong, Li, Li, Hou, Zheng, Lin, Ren: "Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts." in: Inflammation, (2014) (PubMed).

Zhao, Li, Katzenellenbogen, Lau, Taylor, Bagchi, Bagchi: "Estrogen-Induced CCN1 is Critical for Establishment of Endometriosis-like Lesions in Mice." in: Molecular endocrinology (Baltimore, Md.), pp. me20141080, (2014) (PubMed).

Ning, Sun, Hong, Liang, Liu, Han, Liu, Shi, Li, Gong, Zhang, Chen, Guo, Cheng, Wu, Fan: "Calcyclin-binding protein inhibits proliferation, tumorigenicity, and invasion of gastric cancer." in: Molecular cancer research : MCR, Vol. 5, Issue 12, pp. 1254-62, (2008) (PubMed).

Target Details for Factor VIII

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Alternative Name: Factor 8 (F8 Products)

Synonyms: fb61d02 antibody, wu:fb61d02 antibody, Cf-8 antibody, Cf8 antibody, FVIII antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, HEMA antibody, coagulation factor VIIi antibody, coagulation factor VIII antibody, coagulation factor VIII, procoagulant component antibody, f7i antibody, F8 antibody

Background:

Synonyms: AHF, F8B, F8C, HEMA, FVIII, DXS1253E, Coagulation factor VIII, Antihemophilic factor, Procoagulant component, F8

Background: Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.

Gene ID: 2157

UniProt: P00451