Keratin 12 (KRT12) antibody

Details for Product No. ABIN872955, Supplier: Log in to see
Antigen
  • fb05e09
  • wu:fa91b04
  • wu:fa97a07
  • wu:fb05e09
  • k12
  • xk81b2
  • K12
  • AI835216
  • Krt-12
  • Krt1-12
  • Ka12
  • keratin 91
  • keratin 12
  • keratin 12 S homeolog
  • krt91
  • KRT12
  • krt12
  • Krt12
  • krt12.S
Reactivity
Human, Mouse (Murine), Rat (Rattus)
54
26
25
2
1
Host
Rabbit
58
4
1
Clonality
Polyclonal
Conjugate
Un-conjugated
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
44
28
21
16
12
9
3
2
2
1
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from human CK12/Cytokeratin 12
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name CK12 (KRT12 Antibody Abstract)
Background

Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)

Synonyms: 65 kDa cytokeratin, CK 12, CK 3, CK12, CK3, Cytokeratin 12, Cytokeratin 3, K12, K3, keratin 12 Meesmann corneal dystrophy, Keratin 12, Keratin 3, Keratin, type I cytoskeletal 12, K1C12_HUMAN, Keratin, type II cytoskeletal 3, KRT12, KRT3.

Molecular Weight 54kDa
Gene ID 3859
Application Notes IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Supplier Images
SDS-PAGE (SDS) image for anti-Keratin 12 (KRT12) antibody (ABIN872955) Lane 1: rat liver lysates Lane 2: rat brain lysates probed with Anti CK12/Cytokeratin...
Immunohistochemistry (IHC) image for anti-Keratin 12 (KRT12) antibody (ABIN872955) Formalin-fixed and paraffin embedded mouse stomach labeled with Anti-CK12 Polyclonal ...