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STAM antibody (AA 101-200)

STAM Reactivity: Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN873004
  • Target See all STAM Antibodies
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    Binding Specificity
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivity
    • 49
    • 19
    • 8
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Rat
    Host
    • 45
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 49
    • 3
    Polyclonal
    Conjugate
    • 35
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STAM antibody is un-conjugated
    Application
    • 40
    • 22
    • 20
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human STAM
    Isotype
    IgG
    Top Product
    Discover our top product STAM Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    STAM (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 1 (STAM))
    Alternative Name
    STAM (STAM Products)
    Synonyms
    STAM-1 antibody, STAM1 antibody, wu:fv75b10 antibody, zgc:55725 antibody, RGD1564499 antibody, signal transducing adaptor molecule antibody, signal transducing adapter molecule 1 antibody, Signal transducing adapter molecule 1 antibody, signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 antibody, STAM antibody, CpipJ_CPIJ003516 antibody, Tsp_03939 antibody, stam-1 antibody, Stam antibody, stam antibody
    Background

    Synonyms: Signal transducing adapter molecule 1, Signal transducing adapter molecule 2, Signal transducing adaptor molecule SH3 domain and ITAM mot 1, Signal transducing adaptor molecule, STAM 1, STAM-2, STAM1, Stam2, STAM2_HUMAN, DKFZp686J2352, Hrs-binding protein, HSE1 homolog, OTTHUMP00000019237.

    Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

    Gene ID
    8027
    Pathways
    EGFR Signaling Pathway, EGFR Downregulation
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