COMMD7 antibody (AA 81-170)

Catalog No. ABIN873293

Product Details anti-COMMD7 Antibody

Target: COMMD7 (COMM Domain Containing 7 (COMMD7))

Binding Specificity: AA 81-170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COMMD7 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for COMMD7

Target: COMMD7 (COMM Domain Containing 7 (COMMD7))

Alternative Name: COMMD7 (COMMD7 Products)

Synonyms: commd7 antibody, MGC75822 antibody, COMMD7 antibody, LOC100230560 antibody, C20orf92 antibody, dJ1085F17.3 antibody, 2310010I22Rik antibody, AW060956 antibody, mU3 antibody, zgc:101056 antibody, COMM domain containing 7 antibody, commd7 antibody, COMMD7 antibody, LOC100230560 antibody, Commd7 antibody

Background:

Synonyms: C20orf92, Chromosome 20 open reading frame 92, COMM domain containing 7, COMM domain containing protein 7, COMMD 7, dJ1085F17.3, FLJ14987, MGC33315, OTTHUMP00000030609, COMD7_HUMAN.

Background: COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The prototype of this family, MURR1/COMMD1, suppresses NFkB by affecting the association of NF-kappaB with chromatin. COMMD7 (COMM domain-containing protein 7) interacts with COMMD1 via its COMM domain. It also associates with the NF-kappa-B complex and suppresses its transcriptional activity.

Gene ID: 149951