CAMK4 antibody (pThr196, pThr200) (Alexa Fluor 647)

Catalog No. ABIN877683

Product Details anti-CAMK4 Antibody (Alexa Fluor 647)

Target: CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))

Binding Specificity: pThr196, pThr200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK4 antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificity: Phosphorylation site corresponds to Thr200 and Thr204 in human.

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse CAMKIV around the phosphorylation site of Thr196 + Thr200.

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CAMK4

Target: CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))

Alternative Name: Camk4 (CAMK4 Products)

Background:

Synonyms: CAMKIVphospho T196 + T200, Brain Ca2+ calmodulin dependent protein kinase type 4, Brain Ca2+ calmodulin dependent protein kinase type IV, Calcium / calmodulin dependent protein kinase type 4 catalytic chain, Calcium / calmodulin dependent protein kinase type IV catalytic chain, Calcium/calmodulin dependent protein kinase IV, Calcium/calmodulin dependent protein kinase type IV, CAM kinase 4, CAM kinase GR, CAM kinase IV, CaMK 4, CAMK GR, CaMK IV, CaMK4, CaMKGR, MGC36771.

Background: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.

UniProt: P08414

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Production of Molecular Mediator of Immune Response, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma