CARD17 antibody (AA 1-100) (Cy5.5)

Catalog No. ABIN886430

Product Details anti-CARD17 Antibody (Cy5.5)

Target: CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CARD17 antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CARD17/INCA

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CARD17

Target: CARD17 (Caspase Recruitment Domain Family, Member 17 (CARD17))

Alternative Name: CARD17 (CARD17 Products)

Synonyms: INCA antibody, caspase recruitment domain family member 17 antibody, CARD17 antibody

Background:

Synonyms: CAR17_HUMAN, CARD 17, CARD17, Caspase 1 inhibitor, Caspase recruitment domain containing protein 17, Caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, Caspase1 inhibitor, Inhibitory caspase recruitment domain CARD protein, Inhibitory caspase recruitment domain protein.

Background: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.