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CYP46A1 antibody (AA 51-150) (Alexa Fluor 350)

CYP46A1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN893240
  • Target See all CYP46A1 Antibodies
    CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
    Binding Specificity
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 32
    • 27
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This CYP46A1 antibody is conjugated to Alexa Fluor 350
    Application
    • 38
    • 23
    • 23
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CYP46
    Isotype
    IgG
    Top Product
    Discover our top product CYP46A1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
    Alternative Name
    CYP46 (CYP46A1 Products)
    Synonyms
    CP46 antibody, CYP46 antibody, CYP46A1 antibody, zgc:109896 antibody, MGC147389 antibody, Cyp46 antibody, cytochrome P450 family 46 subfamily A member 1 antibody, cytochrome P450 family 46 subfamily A member 1 L homeolog antibody, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 antibody, cytochrome P450, family 46 antibody, cytochrome P450 46A1 antibody, cytochrome P450, family 46, subfamily a, polypeptide 1 antibody, cholesterol 24-hydroxylase antibody, cytochrome P450, family 46, subfamily A, polypeptide 1 antibody, CYP46A1 antibody, cyp46a1.L antibody, cyp46a1.1 antibody, cyp46a1 antibody, PTRG_08343 antibody, PTRG_09667 antibody, Cyp46a1 antibody, Sgly_1093 antibody
    Background

    Synonyms: Cholesterol 24-hydroxylase, CP46, CYP46, CP46A_HUMAN, cytochrome P450 family 46.

    Background: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.

    Gene ID
    10858
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