FAM102B antibody (AA 53-150) (Alexa Fluor 647)

Catalog No. ABIN896109

Product Details anti-FAM102B Antibody (Alexa Fluor 647)

Target: FAM102B (Family with Sequence Similarity 102, Member B (FAM102B))

Binding Specificity: AA 53-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM102B antibody is conjugated to Alexa Fluor 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM102B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FAM102B

Target: FAM102B (Family with Sequence Similarity 102, Member B (FAM102B))

Alternative Name: FAM102B (FAM102B Products)

Synonyms: SYM-3B antibody, 1600010D10Rik antibody, B430201A12Rik antibody, RGD1310037 antibody, si:ch211-199m3.7 antibody, fam102b antibody, zgc:136846 antibody, family with sequence similarity 102 member B antibody, family with sequence similarity 102, member B antibody, family with sequence similarity 102, member B, b antibody, family with sequence similarity 102, member B, a antibody, FAM102B antibody, Fam102b antibody, fam102bb antibody, fam102ba antibody

Background:

Synonyms: F102B_HUMAN, Fam102b, Protein FAM102B.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM102B gene product has been provisionally designated FAM102B pending further characterization.

Gene ID: 284611