HBXIP antibody (AA 41-91) (HRP)

Catalog No. ABIN900211

Product Details anti-HBXIP Antibody (HRP)

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Binding Specificity: AA 41-91

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBXIP antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HBXIP

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HBXIP

Target: HBXIP (Hepatitis B Virus X-Interacting Protein (HBXIP))

Alternative Name: HBXIP (HBXIP Products)

Synonyms: HBXIP antibody, xip antibody, XIP antibody, 1110003H18Rik antibody, Hbxip antibody, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 antibody, Hepatitis B virus X-interacting protein antibody, LAMTOR5 antibody, xip antibody, Lamtor5 antibody

Target Type: Viral Protein

Background:

Synonyms: HBV X interacting protein, HBX interacting protein, Hepatitis B virus X interacting protein, MGC71071, XIP, HBXIP_HUMAN.

Background: HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

Gene ID: 10542

Pathways: PI3K-Akt Signaling, Regulation of Cell Size