IL10RB antibody (PE-Cy5.5)

Catalog No. ABIN902140

This Rabbit Polyclonal antibody specifically detects IL10RB in WB and FACS. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog and Pig.

Quick Overview for IL10RB antibody (PE-Cy5.5) (ABIN902140)

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL10RB antibody is conjugated to PE-Cy5.5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-IL10RB Antibody (PE-Cy5.5)

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IL10RB

Isotype: IgG

Application Details

Application Notes: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for IL10RB

Target: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Alternative Name: IL-10RB/CRFB4

Background:

Synonyms: Interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit beta, IL-10RB, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, CRF2-4, Interleukin-10 receptor subunit 2, IL-10R subunit 2, IL-10R2, CDw210b, IL10RB, CRFB4, D21S58, D21S66

Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

Molecular Weight: 39kDa

Gene ID: 3588

UniProt: Q08334