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Integrin beta 5 antibody (ITGB5) (Alexa Fluor 647) Primary Antibody

ITGB5 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN902971
$442.20
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    Integrin beta 5 (ITGB5)
    Reactivity
    • 68
    • 29
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 57
    • 7
    • 3
    • 2
    Rabbit
    Clonality
    • 68
    • 1
    Polyclonal
    Conjugate
    • 32
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 5 antibody is conjugated to Alexa Fluor 647
    Application
    • 51
    • 39
    • 22
    • 11
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Integrin beta 5
    Isotype
    IgG
  • Application Notes
    IF(IHC-P)(1:50-200)
    Comment

    Exitation/Emission: 652nm/668nm

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at 4°C
    Expiry Date
    12 months
  • Target
    Integrin beta 5 (ITGB5)
    Alternative Name
    Integrin beta 5 (ITGB5 Antibody Abstract)
    Synonyms
    ITGB5, AA475909, AI874634, ESTM23, [b]-5, [b]5, [b]5A, [b]5B, beta-5, beta5, RGD1563276, integrin, beta 5, integrin beta 5, integrin subunit beta 5, ITGB5, Itgb5
    Background

    Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue.


    Synonyms: Integrin beta 5, Integrin beta-5, integrin, beta 5, ITB5_HUMAN, Itgb5, AA475909, AI874634, beta-5, beta5, ESTM23, [b]-5, [b]5, [b]5A, [b]5B FLJ26658, ITGB 5, ITGB5, Integrin i²5.
    Gene ID
    3693
    Pathways
    Integrin Complex
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