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Lamin B Receptor antibody (AA 1-100) (Alexa Fluor 647)

LBR Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN904408
  • Target See all Lamin B Receptor (LBR) Antibodies
    Lamin B Receptor (LBR)
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 27
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 25
    • 2
    Rabbit
    Clonality
    • 25
    • 2
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lamin B Receptor antibody is conjugated to Alexa Fluor 647
    Application
    • 26
    • 13
    • 6
    • 6
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Specificity
    The immunogen for this product has partial sequence similarity to SEPT8 and SEPT2
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Cow,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Lamin B Receptor
    Isotype
    IgG
  • Application Notes
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Lamin B Receptor (LBR)
    Alternative Name
    Lamin B Receptor (LBR Products)
    Synonyms
    CG17952 antibody, Dmel\\CG17952 antibody, dLBR antibody, sb:cb406 antibody, zgc:86649 antibody, wu:fb75h08 antibody, wu:fc47b04 antibody, wu:fd36b07 antibody, lbr-A antibody, Xp58 antibody, p58 gene antibody, LBR antibody, DHCR14B antibody, LMN2R antibody, PHA antibody, TDRD18 antibody, AI505894 antibody, ic antibody, Nbp60 antibody, lamin B receptor antibody, Lamin B receptor antibody, lamin B receptor S homeolog antibody, LBR antibody, lbr antibody, lbr.S antibody, Lbr antibody
    Background

    Synonyms: PHA, LMN2R, TDRD18, DHCR14B, Lamin-B receptor, Integral nuclear envelope inner membrane protein, LBR

    Background: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.

    Gene ID
    3930
    UniProt
    Q14739
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